Structure-antibacterial activity relationship of some aromatic acids

Quantitative structure-activity relationship of some pesticides.

Herbicides (benzodiazepinediones), insecticides (dioxatricyclododecenes) and larvicides (N-oxalyl derivatives of tebufenozide) have been quantitatively investigated to explore the relationship between the molecular structure and their biological activity using molecular operating environment (MOE) software. The study provides good predictive models, cross-validated by leave-out-one method (Loo)...

Antibacterial Screening of Some Synthesized Palmitoyl Amino Acids and Their Aromatic Analogues

Aims: The aims of the research were to synthesize, characterize some palmitoyl amino acids and their aromatic analogues and to screen the synthesized compounds for possible antibacterial activity Study Design: Synthesis, characterization and antibacterial screening of palmitoyl amino acids and their aromatic analogues. Place and Duration of Study: Department of Pharmaceutical and Medicinal Chem...

Structure- Activity Relationship (Sar) Of Cyanoethylated Aromatic Amines

Two types of aromatic amines were cyanoethylated. The cyano ethylated products were reacted with propylene oxide to give azocomponents: N-acetyl – N – β – hydroxyl propyl, Nβ-propylnitrile -1, 3 – phenyl diamine and Nβ hydroxypropyl, Nβpropyl nitrile aniline. These products are referred to as Azodin A and Azodin B respectively. When diazotized aromatic amines were coupled to Azodin B, eight dye...

Relationship between structure and antibacterial activity of lipophilic N-acyldiamines.

We report in this work the preparation and antibacterial evaluation of a series of N-monoacylated diamines against six Gram-positive and 11 Gram-negative bacteria. The results obtained showed the existence of relationship between lipophilicity and antibacterial activity of the tested compounds. The best results were obtained against Gram-positive bacteria for compounds having a 10-12 carbons al...

Antibacterial Activity of Some New Azole Compounds